Episode 29: What is the Physiology and Neurobiology of the Trauma Response? with Dr. Aimie Apigian
- THA Operations
- 4 days ago
- 4 min read
What's Actually Happening in Your Body
Everyone talks about trauma constantly. Therapists use the word, self-help books discuss it, and social media posts reference it repeatedly. But most people have no idea what trauma actually means in biological terms.
Understanding the physiology and neurobiology changes everything about how you approach healing. When you know what's happening in your body, you stop blaming yourself for responses you can't control.
Trauma gets thrown around as a concept without clear definition. But what does it actually mean in your body? The answer lies in your physiology and neurobiology.
Today I break down the foundational biological aspects of trauma, what you need to know to understand your trauma responses, and what you can actually do about it.
The Biology Behind the Word
Trauma isn't just what happened to you in the past. It's what happens inside your body as a result of those experiences. Your cells respond to overwhelming events. Your nervous system adapts to protect you. Your biology changes at fundamental levels.
Your body follows a precise five-step sequence during trauma: startle, stress, powerlessness, freeze, and shutdown. This is universal across all humans. Everyone's nervous system uses this same pathway when overwhelmed because it's hardwired into our biology.
The neurobiology involved operates automatically without conscious choice. Your amygdala detects threat before your conscious mind registers it. Your prefrontal cortex goes offline when threat is detected. Your brainstem takes over to manage survival responses. This is automatic biology, not a decision you make or a weakness you possess.
Your body's trauma response exists to protect you from harm. Heart rate changes to prepare for action. Blood flow redirects to muscles needed for escape. Hormones flood your system to support survival. This response saved your life when you faced actual danger and it's doing exactly what evolution designed it to do.
Why Your Body Stays Stuck
When trauma doesn't complete its biological cycle, your body holds the protective pattern. Your nervous system stays in that defensive state even when the threat is long gone. Your biology keeps running the same program because it never received the signal that the danger passed.
There's an invisible line between growth and breakdown that I call the Critical Line. Trauma happens when demands exceed your capacity and you cross that line into overwhelm. Understanding this concept changes how you approach healing because you recognize that trauma isn't about the event itself but about your capacity to handle it at that moment.
What you can do about stored trauma doesn't involve thinking your way out of it. You can't use logic or understanding alone to change trauma biology. But you can work with your nervous system directly through regulation practices, build capacity gradually through small doses of activation, support your body's natural healing processes, and teach your biology that it's safe to complete the protective responses it started.
Why Foundational Knowledge Matters
Understanding what's happening in your body removes the shame that trauma survivors carry. These aren't personal failures or signs of weakness. They're biological responses that make complete sense when you understand the physiology and neurobiology involved.
Your brain regions communicate in specific ways during trauma that affect your entire experience. The amygdala becomes hyperactive and scans constantly for threat. The hippocampus struggles to contextualize memories properly. The prefrontal cortex loses its ability to regulate emotional responses. The brainstem controls survival behaviors without higher brain input.
The physiology of protection involves your entire body's systems. Your sympathetic nervous system activates for fight or flight responses. Your dorsal vagal complex triggers freeze and shutdown. Your HPA axis floods your system with cortisol. Your cardiovascular system redirects blood flow. Your digestive system shuts down. Your immune system shifts resources.
When you understand the Biology of Trauma® at this foundational level, you stop asking "what's wrong with me?" and start asking "what happened to me and how did my body respond?" That shift from shame to understanding opens the door to actual healing because you're working with your biology instead of fighting against it.
This Episode Is For:
✓ Anyone who wants to understand what trauma actually is biologically
✓ People tired of vague trauma language without clear explanations
✓ Practitioners needing clear foundational concepts to explain to clients
✓ Those who want to understand why their body responds the way it does
✓ Anyone ready to learn the science behind trauma responses
✓ People who learn better when they understand the mechanism
What You'll Learn
Listen to understand the physiology and neurobiology of trauma and what actually happens in your body during traumatic experiences. Discover the five-step trauma response sequence that all humans share. Learn why knowing this biological foundation changes how you approach your own healing.
Your trauma responses make perfect biological sense when you understand what's happening beneath the surface.
Disclaimer
This podcast is for educational purposes only and is not a substitute for professional medical or mental health advice, diagnosis, or treatment. The information shared reflects my clinical expertise and research, but every person's biology and healing journey is unique. Always consult with qualified healthcare providers before making changes to your treatment plan or starting new interventions. If you're experiencing a mental health crisis, please contact emergency services or a crisis helpline immediately.
Join the Conversation
I'd love to hear your thoughts on this episode. What resonated with you? What questions came up?
Please keep comments respectful and supportive. This is a community of people committed to healing. We welcome diverse perspectives and honest questions, but we don't tolerate personal attacks, spam, or content that could harm others on their healing journey.




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